Description: The Transducin-like enhancer protein 1 (TLE1) can recruit a wide range of transcriptional repressors via its WD domain, to which the WRPW motif of Transcription factor HES-1 (HES1) and the EH1 motif of Homeobox protein goosecoid (GSC) can bind using overlapping sites.
Participants: (1) Transcription factor HES-1 (HES1) (2) Transducin-like enhancer protein 1 (TLE1) (3) Homeobox protein goosecoid (GSC)
(1) Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE corepressor.Jennings et al. Mol. Cell (2006)
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