Description: Phosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Participants: (1) Transcription factor AP-1 (JUN) (2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)
(1) Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.Wulf et al. EMBO J. (2001)
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