Description: Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Growth factor receptor-bound protein 7 (GRB7) protein.
Participants: (1) Receptor tyrosine-protein kinase erbB-2 (ERBB2) (2) Growth factor receptor-bound protein 7 (GRB7)
(1) Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2.Ivancic et al. J. Biomol. NMR (2003)
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