Description: Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).
Participants: (1) GRB2-associated-binding protein 1 (GAB1) (2) Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1)
(1) Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.Lehr et al. Biochemistry (2000)
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