Description: Participants: Interactions Interaction #1 LMP2 - Itch Interfaces (1) LIG_WW_1 motif (98PPPY101) in Latent membrane protein 2 (LMP2) (2) WW domain (319-352) in E3 ubiquitin-protein ligase Itchy (Itch) Interaction Regulation Alternative splicing Abrogation of the Latent membrane protein 2 (LMP2) LIG_WW_1 motif - E3 ubiquitin-protein ligase Itchy (Itch) WW domain interaction Context Switch localisation ELM curated: cytosol, integral membrane protein, integral plasma membrane protein References (1) NMR structural studies of the ItchWW3 domain reveal that phosphorylation at T30 inhibits the interaction with PPxY-containing ligands. |
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