Description: Phosphorylation of Y757 in the SH2-binding motif of Interleukin-6 receptor subunit beta (Il6st) induces binding to the Suppressor of cytokine signaling 3 (Socs3) protein.
Participants: (1) Interleukin-6 receptor subunit beta (Il6st) (2) Suppressor of cytokine signaling 3 (Socs3)
(1) The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.Babon et al. Mol. Cell (2006)
