Switch #:
SWTI000441
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of Y246 in the SH2-binding motif of Guanine nucleotide-binding protein subunit beta-2-like 1 (Gnb2l1) induces binding to the Proto-oncogene tyrosine-protein kinase Src (SRC) protein.

Participants:
(1) Guanine nucleotide-binding protein subunit beta-2-like 1 (Gnb2l1)
(2) Proto-oncogene tyrosine-protein kinase Src (SRC)

Interactions
Context
Switch localisation
References

(1) RACK1 regulates G1/S progression by suppressing Src kinase activity.
Mamidipudi et al. Mol. Cell. Biol. (2004)




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