Description: Phosphorylation of Y402 in the SH2-binding motif of Protein-tyrosine kinase 2-beta (PTK2B) induces binding to the Megakaryocyte-associated tyrosine-protein kinase (MATK) protein.
Participants: (1) Protein-tyrosine kinase 2-beta (PTK2B) (2) Megakaryocyte-associated tyrosine-protein kinase (MATK)
(1) Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration.McShan et al. Int. J. Oncol. (2002)
