Description: Phosphorylation of Y196 in the SH2-binding motif of Fibroblast growth factor receptor substrate 2 (FRS2) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
Participants: (1) Fibroblast growth factor receptor substrate 2 (FRS2) (2) Growth factor receptor-bound protein 2 (GRB2)
(1) Fibroblast growth factor receptor 1 (FGFR1) tyrosine phosphorylation regulates binding of FGFR substrate 2alpha (FRS2alpha) but not FRS2 to the receptor.Zhang et al. Mol. Endocrinol. (2008)
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