Description: Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Ras and Rab interactor 1 (RIN1) protein.
Participants: (1) Epidermal growth factor receptor (EGFR) (2) Ras and Rab interactor 1 (RIN1)
(1) The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosis.Barbieri et al. J. Biol. Chem. (2003)
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