Description: Phosphorylation of Y235 in the SH2-binding motif of Linker for activation of T-cells family member 1 (Lat) induces binding to the Growth factor receptor-bound protein 2 (Grb2) protein.
Participants: (1) Linker for activation of T-cells family member 1 (Lat) (2) Growth factor receptor-bound protein 2 (Grb2)
(1) Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.Zhang et al. J. Biol. Chem. (2000)
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