Description: Phosphorylation of S411 in the PDZ-binding motif of Beta-2 adrenergic receptor (ADRB2) by inhibits its interaction with the Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1) protein.
Participants: (1) Beta-2 adrenergic receptor (ADRB2) (2) Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1)
(1) A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.Cao et al. Nature (1999)
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