Description: Phosphorylation of T743 adjacent to the PTB-binding motif of Amyloid beta A4 protein (APP) reduces the affinity for Amyloid beta A4 precursor protein-binding family B member 1 (APBB1).
Participants: (1) Amyloid beta A4 protein (APP) (2) Amyloid beta A4 precursor protein-binding family B member 1 (APBB1)
(1) Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.Radzimanowski et al. EMBO Rep. (2008)
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