Description: Participants: Interactions Interaction #1 HIF1A - Crebbp Interfaces (1) ELM:LIG_TAZ1 motif (792LPQL795) in Hypoxia-inducible factor 1-alpha (HIF1A) (2) TAZ zinc finger (351-431) in CREB-binding protein (Crebbp) Interaction Regulation PTM-dependent Abrogation (Hydroxylation of N803 on Hypoxia-inducible factor 1-alpha (HIF1A)) of the Hypoxia-inducible factor 1-alpha (HIF1A) LIG_TAZ1 motif - CREB-binding protein (Crebbp) TAZ zinc finger interaction Regulatory Enzymes for switch Modifying enzymes for residue: N803: Hypoxia-inducible factor 1-alpha inhibitor (HIF1AN) Additional Information Structural information: 1L8C Context References (1) Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. |
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