Description: Phosphorylation of S208 in the Pin1-binding motif of Mothers against decapentaplegic homolog 3 (SMAD3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Participants: (1) Mothers against decapentaplegic homolog 3 (SMAD3) (2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)
(1) Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.Nakano et al. J. Biol. Chem. (2009)
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