Description: Phosphorylation of T187 in the Pin1-binding motif of Cyclin-dependent kinase inhibitor 1B (CDKN1B) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Participants: (1) Cyclin-dependent kinase inhibitor 1B (CDKN1B) (2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)
(1) Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process.Zhou et al. J. Biol. Chem. (2009)
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