Description: Phosphorylation of S434 in the Pin1-binding motif of Insulin receptor substrate 1 (IRS1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Participants: (1) Insulin receptor substrate 1 (IRS1) (2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)
(1) Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with insulin receptor substrate-1 and enhances insulin actions and adipogenesis.Nakatsu et al. J. Biol. Chem. (2011)
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