Description: Phosphorylation of Transcription factor AP-1 (JUN) at S243 primes the protein for phosphorylation at T239 by Glycogen synthase kinase-3 beta (GSK3B).
Participants: (1) Transcription factor AP-1 (JUN) (2) Glycogen synthase kinase-3 beta (GSK3B)
(1) Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.Boyle et al. Cell (1991)
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